Uricase

• Name: Urate: oxygen oxidoreductase
• Appearance: white amorphous powder lyophilized
• Activity: Grade II, 4.0U/mg-solid or more (containing approx.20% of stabilizers)
• Contaminants: Catalase ≤ 1.0%
• Stabilizers: Borate, EDTA, nonionic detergents
• Stability: Stable at －20℃ for at least one year
• Molecular weight: approx. 120,000
• Structure: 4 subunits per molecule (Reactive SH groups are present in the enzyme molecule)
• Isoelectric point: 5.4
• Michaelis constant: 2.5×10^-5 M (Uric acid)
• Inhibitors: Heavy metal ions, cyanide,various urate analogs
• Optimum pH: 8.5
• Optimum temperature: 40℃
• pH Stability: pH 7.0－11.0 (25℃, 20hr)
• Thermal stability: below 50℃ (pH 8.5, 10min)

EC # 1.7.3.3